metronidazole will raise the degree or result of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
Ask your physician When you've got questions about sorts of birth control that may be just right for you. Should you or your husband or wife grow to be Expecting while employing bortezomib or for seven months just after your last dose, simply call your physician promptly.
Acute respiratory distress syndrome (ARDS) and acute diffuse infiltrative pulmonary sickness of mysterious etiology for example pneumonitis, interstitial pneumonia, lung infiltration have occurred
fluvoxamine will boost the degree or result of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
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explain to your medical professional and Health care provider When you are allergic to bortezomib, mannitol, some other medicines, boron, or any of your components in bortezomib. Talk to your healthcare company for an index of the ingredients.
ponesimod and Bortezomib bortezomib the two raise immunosuppressive consequences; hazard of an infection. Use Warning/Observe. Warning if coadministered because of additive immunosuppressive effects in the course of these therapy and during the months next administration.
bortezomib decreases outcomes 3'-cGAMP sodium of clopidogrel by reducing metabolism. Use Caution/Keep an eye on. Steer clear of concurrent use of CYP2C19 inhibitors with clopidogrel. As a result of thrombocytopenic results of bortezomib, an additive chance of bleeding may very well be found in individuals receiving concomitant platelet inhibitors.
zafirlukast will increase the level or effect of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
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cimetidine will enhance the stage or result of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
efavirenz will lower the level or outcome of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
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Indicated for procedure of clients with mantle mobile lymphoma as 1st-line in previously untreated sufferers or anyone who has relapsed